Summary

Name PPFIA2
Full Name Liprin-alpha-2
Synonyms Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2, PTPRF-interacting protein alpha-2 |
Primary ID O75334
Links - -
Type protein
Relations 1
Function Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates. In neuronal cells, is a scaffolding protein in the dendritic spines which acts as immobile postsynaptic post able to recruit KIF1A-driven dense core vesicles to dendritic spines (PubMed:30021165).

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Relations

Regulator Mechanism target score ℹ
+ R2SP co-chaperoneup-regulates quantity by stabilization img/direct-activation.png binding PPFIA2 0.2
Publications: 1 Organism: Homo Sapiens