Name FOXH1
Full Name Forkhead box protein H1
Synonyms Forkhead activin signal transducer 1, Fast-1, hFAST-1, Forkhead activin signal transducer 2, Fast-2 | FAST1, FAST2
Primary ID O75593
Links - -
Type protein
Relations 1
Function Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).



Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding SMAD2 0.70
Publications: 1 Organism: Homo Sapiens