Summary

Name UGT2B17
Full Name UDP-glucuronosyltransferase 2B17
Synonyms UDPGT 2B17, C19-steroid-specific UDP-glucuronosyltransferase, C19-steroid-specific UDPGT |
Primary ID O75795
Links - -
Type protein
Relations 0
Function UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile (PubMed:8798464, PubMed:16595710, PubMed:18719240, PubMed:19022937, PubMed:23288867). Catalyzes the glucuronidation of endogenous steroid hormones such as androgens (epitestosterone, androsterone) and estrogens (estradiol, epiestradiol) (PubMed:8798464, PubMed:16595710, PubMed:18719240, PubMed:19022937, PubMed:23288867).

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