Summary

Name BCAS2
Full Name Pre-mRNA-splicing factor SPF27
Synonyms Breast carcinoma-amplified sequence 2, DNA amplified in mammary carcinoma 1 protein, Spliceosome-associated protein SPF 27 | DAM1
Primary ID O75934
Links - -
Type protein
Relations 1
Function Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961, PubMed:30705154). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

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Relations

Regulator Mechanism target score ℹ
+ BCAS2form complex img/form-complex.png binding PRP19-CDC5L 0.89
Publications: 1 Organism: Homo Sapiens