Name
|
CDK2AP2
|
Full Name |
Cyclin-dependent kinase 2-associated protein 2 |
Synonyms |
CDK2-associated protein 2, DOC-1-related protein, DOC-1R | DOC1R |
Primary ID |
O75956 |
Links |
- -  |
Type |
protein |
Relations |
0 |
Function |
Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes (By similarity). Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A (PubMed:23781148). |