Summary

Name DPM2
Full Name Dolichol phosphate-mannose biosynthesis regulatory protein
Synonyms Dolichol-phosphate mannose synthase subunit 2, DPM synthase subunit 2 |
Primary ID O94777
Links - -
Type protein
Relations 1
Function Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:10835346). Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:10835346). Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis (PubMed:16162815). May act by regulating the GPI-GNT complex (PubMed:10944123).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding DPM complex 0.779
Publications: 1 Organism: Homo Sapiens