Summary

Name ACSL3
Full Name Long-chain-fatty-acid--CoA ligase 3
Synonyms Long-chain acyl-CoA synthetase 3, LACS 3 | ACS3, FACL3, LACS3
Primary ID O95573
Links - -
Type protein
Relations 0
Function Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490). Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins) (PubMed:18003621). Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity (By similarity).

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