+ |
MAP4K4 | down-regulates activity
phosphorylation
|
SMAD1 |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-276335 |
Thr322 |
SNVNRNStIENTRRH |
Homo sapiens |
HEK-293T Cell |
pmid |
sentence |
21690388 |
Msn kinases directly phosphorylate α-helix 1 of Smad. we have identified Misshapen (Msn) and the mammalian orthologs TNIK, MINK1, and MAP4K4 as the kinases responsible for α-helix 1 phosphorylation. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
MAP4K4 | up-regulates
binding
|
MAP3K7 |
0.558 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-77404 |
|
|
Homo sapiens |
|
pmid |
sentence |
10807933 |
The existence of an at least trimolecular complex consisting of nik, tak1, and ikk2, although the precise sequence of activation as well as the possible location of the kinases within the signalosome remains to be elucidated. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
MAP4K4 | up-regulates
phosphorylation
|
MAP3K1 |
0.533 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-44040 |
|
|
Homo sapiens |
|
pmid |
sentence |
8824585 |
Hpk1 binds and phosphorylates mekk1 directly |
|
Publications: |
1 |
Organism: |
Homo Sapiens |