Summary

Name LTA
Full Name Lymphotoxin-alpha
Synonyms LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1 | TNFB, TNFSF1
Primary ID P01374
Links - -
Type protein
Relations 1
Function Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding LTBR 0.837
Publications: 1 Organism: Homo Sapiens