Summary

Name PLA2G1B
Full Name Phospholipase A2
Synonyms Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B | PLA2, PLA2A, PPLA2
Primary ID P04054
Links - -
Type protein
Relations 2
Inhibitors Varespladib
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png chemical inhibition PLA2G1B 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding PLA2G1B 0.14
Publications: 1 Organism: Homo Sapiens