3.0
Summary
| Name |  GP1BAView Modifications |
| Full Name | Platelet glycoprotein Ib alpha chain |
| Synonyms | GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha | |
| Primary ID | P07359 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ADAM17 | down-regulates activity 
cleavage
|
GP1BA | 0.288 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | GP1BA | form complex 
binding
|
GPIb-IX-V complex | 0.697 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RUNX1 | up-regulates quantity by expression 
transcriptional regulation
|
GP1BA | 0.376 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | GATA1 | up-regulates quantity by expression
transcriptional regulation
|
GP1BA | 0.527 |
| Publications: | 1 | Organism: | Homo Sapiens | |