4.0
Summary
| Name |  RHOC
|
| Full Name | Rho-related GTP-binding protein RhoC |
| Synonyms | Rho cDNA clone 9, h9 | ARH9, ARHC |
| Primary ID | P08134 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PAK6 | down-regulates activity 
phosphorylation
|
RHOC | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | RAP1GDS1 | up-regulates 
binding
|
RHOC | 0.298 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | DRAM2 | up-regulates quantity by expression 
transcriptional regulation
|
RHOC | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | hsa-miR-493-5p | down-regulates quantity by repression
post transcriptional regulation
|
RHOC | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |