Relation Results

Summary

Name C1S
Full Name Complement C1s subcomponent
Synonyms C1 esterase, Complement component 1 subcomponent s |
Primary ID P09871
Links - -
Type protein
Relations 1
Function C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r ...
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Type: Score: Layout: SPV 
0.702C1SComplement C1 complex

Relations

Regulator
Mechanism
target
score
+ form complex img/form-complex.png binding Complement C1 complex 0.702
Identifier Residue Sequence Organism Cell Line
SIGNOR-263394 in vitro
pmid sentence
The complement system is part of our innate immune system. The classical complement pathway is triggered by activation of the C1 initiation complex upon binding to cell surfaces. C1, or C1qr2s2, consists of four proteases, C1r and C1s, that associate with C1q, which contains antibody-binding sites.|The reconstruction reveals densities for all C1q collagen-like triple helices and gC1q modules, C1r and C1s proteases
Publications: 1 Organism: In Vitro
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