Summary

Name HNRNPL
Full Name Heterogeneous nuclear ribonucleoprotein L
Synonyms hnRNP L | HNRPL
Primary ID P14866
Links - -
Type protein
Relations 1
Function Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed:11809897, PubMed:22570490, PubMed:24164894, PubMed:25623890, PubMed:26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts (PubMed:2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PubMed:11809897).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation HNRNPL 0.395
Publications: 1 Organism: Homo Sapiens