Summary

Name RPL13
Full Name 60S ribosomal protein L13
Synonyms Breast basic conserved protein 1, Large ribosomal subunit protein eL13 | BBC1
Primary ID P26373
Links - -
Type protein
Relations 1
Function Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:31630789, PubMed:23636399). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs (PubMed:31630789). Plays a role in bone development (PubMed:31630789).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding 60S cytosolic large ribosomal subunit 0.778
Publications: 1 Organism: In Vitro