3.0
Summary
| Name |  NDUFS1
|
| Full Name | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
| Synonyms | Complex I-75kD, CI-75kD | |
| Primary ID | P28331 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Inhibitors | metformin |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
binding
chemical inhibition