Summary

Name SLC6A1
Full Name Sodium- and chloride-dependent GABA transporter 1
Synonyms GAT-1, Solute carrier family 6 member 1 | GABATR, GABT1, GAT1
Primary ID P30531
Links - -
Type protein
Relations 5
Inhibitors 85375-15-1; tiagabine; 1-(4,4-diphenylbut-3-enyl)-3-piperidinecarboxylic acid; 1-[2-[(diphenylmethylene)amino]oxyethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid; 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid
Function Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png chemical inhibition SLC6A1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png chemical inhibition SLC6A1 0.14
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png chemical inhibition SLC6A1 0.14
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png chemical inhibition SLC6A1 0.14
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png chemical inhibition SLC6A1 0.14
Publications: 1 Organism: In Vitro