Relation Results

Summary

Name CHI3L1
Full Name Chitinase-3-like protein 1
Synonyms 39 kDa synovial protein, Cartilage glycoprotein 39, CGP-39, GP-39, hCGP-39, YKL-40
Primary ID P36222
Links - -
Type protein
Relations 1
Function Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells ...
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Type: Score: Layout: SPV 
0.284STAT6CHI3L1

Relations

Regulator
Mechanism
target
score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CHI3L1 0.284
Identifier Residue Sequence Organism Cell Line
SIGNOR-249537 Homo sapiens Macrophage
pmid sentence
Phosphorylated STAT6 dimerizes and translocates to the nucleus where it induces the expression of its target genes, including markers (Arg1, Chi3l3, Mrc1, Mgl1, and Retnla) and regulators (Pparalpha, Ppargamma and PGC-1?) of alternative activation.
Publications: 1 Organism: Homo Sapiens
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