Summary

Name PSMB10
Full Name Proteasome subunit beta type-10
Synonyms Low molecular mass protein 10, Macropain subunit MECl-1, Multicatalytic endopeptidase complex subunit MECl-1, Proteasome MECl-1, Proteasome subunit beta-2i | LMP10, MECL1
Primary ID P40306
Links - -
Type protein
Relations 1
Inhibitors carfilzomib
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png chemical inhibition PSMB10 0.8
Publications: 1 Organism: Homo Sapiens