3.0
Summary
| Name |  NSFView Modifications |
| Full Name | Vesicle-fusing ATPase |
| Synonyms | N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF |
| Primary ID | P46459 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | LRRK2 | up-regulates activity 
phosphorylation
|
NSF | 0.375 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPN9 | down-regulates 
dephosphorylation
|
NSF | 0.422 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | NSF | down-regulates activity
binding
|
SNAP25 | 0.746 |
| Publications: | 1 | Organism: | Homo Sapiens | |