Summary

Name KCNJ5
Full Name G protein-activated inward rectifier potassium channel 4
Synonyms GIRK-4, Cardiac inward rectifier, CIR, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, IRK-4, KATP-1, Potassium channel, inwardly rectifying subfamily J member 5 | GIRK4
Primary ID P48544
Links - -
Type protein
Relations 1
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding KCNJ5/KCNJ3 0.481
Publications: 1 Organism: Homo Sapiens
Tissue: Heart