Summary

Name PGF
Full Name Placenta growth factor
Synonyms PlGF | PGFL, PLGF
Primary ID P49763
Links - -
Type protein
Relations 1
Inhibitors Aflibercept
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

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Relations

Regulator Mechanism target score ℹ
+ Afliberceptdown-regulates activity img/direct_inhibition.png chemical inhibition PGF 0.8
Publications: 1 Organism: Homo Sapiens