Summary

Name DNM2
Full Name Dynamin-2
Synonyms DYN2_HUMAN | DYN2
Primary ID P50570
Links - -
Type protein
Relations 9
Function Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png dephosphorylation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ img/unknown.png dephosphorylation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ img/unknown.png dephosphorylation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ img/unknown.png dephosphorylation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates img/direct-activation.png binding MYO1C
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding GJB2 0.19
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation DNM2
Publications: 1 Organism: Rattus Norvegicus
+ up-regulates img/direct-activation.png binding DNM2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png binding DNM2 0.53
Publications: 1 Organism: Homo Sapiens