Summary

Name CLCN4
Full Name H(+)/Cl(-) exchange transporter 4
Synonyms Chloride channel protein 4, ClC-4, Chloride transporter ClC-4 |
Primary ID P51793
Links - -
Type protein
Relations 1
Function Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (PubMed:18063579, PubMed:28972156, PubMed:23647072, PubMed:27550844, PubMed:25644381). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (PubMed:29845874). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (PubMed:29845874).

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Relations

Regulator Mechanism target score ℹ
+ CLCN4down-regulates quantity img/direct_inhibition.png relocalization chloride 0.8
Publications: 1 Organism: Homo Sapiens