Relation Results

Summary

Name SEC24C
Full Name Protein transport protein Sec24C
Synonyms SEC24-related protein C | KIAA0079
Primary ID P53992
Links - -
Type protein
Relations 2
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has ...
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Type: Score: Layout: SPV 
0.7090.692SAR1ASEC24CCOPII vesicle

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Relations
Regulator
Mechanism
target
score ℹ
+ SAR1Aup-regulates quantity img/direct-activation.png binding SEC24C 0.709
Identifier Residue Sequence Organism Cell Line
SIGNOR-265302
pmid sentence
Biogenesis of COPII vesicles is initiated by the activation of the small guanosine triphosphate (GTP)-binding protein secretion-associated Ras-related protein 1 (Sar1) at specialized subdomains of the ER, called ER exit sites (ERES) or transitional ER (tER). Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer.
Publications: 1
+ SEC24Cform complex img/form-complex.png binding COPII vesicle 0.692
Identifier Residue Sequence Organism Cell Line
SIGNOR-265294 Homo sapiens HeLa Cell
pmid sentence
The Core Components of COPII Vesicles from HeLa Cells|Membrane-bound Sar1 then recruits the inner COPII coat subcomplex, the Sec23/24 heterodimer. Subsequently, together with cargo proteins recruited by the Sec24 subunit, Sar1 and Sec23/24 assemble into so-called pre-budding complexes. Finally, outer coat subcomplexes, comprising heterotetrameric Sec13/31 complexes, are recruited onto pre-budding complexes to complete the two-layered COPII coat
Publications: 1 Organism: Homo Sapiens
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