Summary

Name SEC24C
Full Name Protein transport protein Sec24C
Synonyms SEC24-related protein C | KIAA0079
Primary ID P53992
Links - -
Type protein
Relations 2
Function Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (PubMed:10214955, PubMed:17499046, PubMed:18843296, PubMed:20427317). Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B (PubMed:17499046, PubMed:20427317, PubMed:18843296). May more specifically package GPI-anchored proteins through the cargo receptor TMED10 (PubMed:20427317). May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5 (PubMed:18843296).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png binding SEC24C 0.698
Publications: 1
+ form complex img/form-complex.png binding COPII vesicle 0.683
Publications: 1 Organism: Homo Sapiens