| + |
HOXC10 | up-regulates quantity by expression 
transcriptional regulation
|
LAMB2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261645 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
| pmid |
sentence |
| 10835276 |
The specificity of binding of these two proteins to the Lamin B2 origin is confirmed by both band-shift and in vitro footprinting assays. In addition, the ability of HOXC10 and HOXC13 to increase the activity of a promoter containing the 74 bp sequence, as assayed by CAT-assay experiments, demonstrates a direct interaction of these homeoproteins with the origin sequence in mammalian cells. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
LAMB2 | form complex 
binding
|
Laminin-9 |
0.54 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253224 |
|
|
|
|
| pmid |
sentence |
| 10809728 |
Laminins are a large family of heterotrimeric extracellular matrix glycoproteins that, in addition to having structural roles, take part in the regulation of processes such as cell migration, differentiation, and proliferation. The laminin alpha(4) chain is widely distributed both in adults and during development in tissues such as cardiac, skeletal and smooth muscle fibers, vascular endothelia, lungs, and in peripheral nerves. It can associate with laminin beta(1)/gamma(1) chains to form laminin-8 and with the beta(2)/gamma(1) chains to form laminin-9. |
|
| Publications: |
1 |
| + |
HOXC13 | up-regulates quantity by expression
transcriptional regulation
|
LAMB2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-261644 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
| pmid |
sentence |
| 10835276 |
The specificity of binding of these two proteins to the Lamin B2 origin is confirmed by both band-shift and in vitro footprinting assays. In addition, the ability of HOXC10 and HOXC13 to increase the activity of a promoter containing the 74 bp sequence, as assayed by CAT-assay experiments, demonstrates a direct interaction of these homeoproteins with the origin sequence in mammalian cells. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
3.0
LAMB2
- 
- 