Summary

Name RAG2
Full Name V
Synonyms RAG-2
Primary ID P55895
Links - -
Type protein
Relations 2
Function Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png relocalization MTOR 0.272
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png RAG2 0.7
Publications: 1 Organism: Homo Sapiens