| Name
|
 UBASH3A
|
| Full Name |
Ubiquitin-associated and SH3 domain-containing protein A |
| Synonyms |
Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1 | STS2 |
| Primary ID |
P57075 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
0 |
| Function |
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. |
4.0