Summary

Name NUTF2
Full Name Nuclear transport factor 2
Synonyms NTF-2, Placental protein 15, PP15 | NTF2
Primary ID P61970
Links - -
Type protein
Relations 1
Function Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding NUP62 0.841
Publications: 1 Organism: Homo Sapiens