Summary

Name LSM6
Full Name U6 snRNA-associated Sm-like protein LSm6
Synonyms LSM6_HUMAN |
Primary ID P62312
Links - -
Type protein
Relations 1
Function Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable).

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Relations

Regulator Mechanism target score ℹ
+ LSM6form complex img/form-complex.png binding U4/U6.U5 snRNP complex 0.791
Publications: 1 Organism: Homo Sapiens