Summary

Name MN1
Full Name Transcriptional activator MN1
Synonyms Probable tumor suppressor protein MN1
Primary ID Q10571
Links - -
Type protein
Relations 5
Function Transcriptional activator which specifically regulates expression of TBX22 in the posterior region of the developing palate. Required during later stages of palate development for growth and medial fusion of the palatal shelves. Promotes maturation and normal function of calvarial osteoblasts, including expression of the osteoclastogenic cytokine TNFSF11/RANKL. Necessary for normal development of the membranous bones of the skull (By similarity). May play a role in tumor suppression (Probable).

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Relations

Regulator Mechanism target score ℹ
+ EP300up-regulates img/direct-activation.png binding MN1 0.348
Publications: 1 Organism: Homo Sapiens
+ MN1up-regulates activity img/direct-activation.png binding MYBBP1A 0.2
Publications: 1 Organism: In Vitro
+ MN1down-regulates img/indirect_inhibition.png Differentiation 0.7
Publications: 1 Organism: Mus Musculus
+ MN1up-regulates img/indirect-activation.png Proliferation 0.7
Publications: 1 Organism: Mus Musculus
+ MN1up-regulates activity img/direct-activation.png binding EP300 0.348
Publications: 1 Organism: In Vitro