4.0
Summary
| Name |  GCKR
|
| Full Name | Glucokinase regulatory protein |
| Synonyms | GKRP, Glucokinase regulator | |
| Primary ID | Q14397 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Regulates glucokinase (GCK) by forming an inactive complex with this enzyme (PubMed:23621087, PubMed:23733961). Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10456334). The affinity of GCKR for GCK is modulated by fructose metabolites |