Summary

Name FXYD3
Full Name FXYD domain-containing ion transport regulator 3
Synonyms Chloride conductance inducer protein Mat-8, Mammary tumor 8 kDa protein, Phospholemman-like | MAT8, PLML
Primary ID Q14802
Links - -
Type protein
Relations 0
Function Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell (PubMed:17077088). Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 (PubMed:21454534). Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes (PubMed:7836447).

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