3.0
Summary
| Name |  UBXN2BView Modifications |
| Full Name | UBX domain-containing protein 2B |
| Synonyms | NSFL1 cofactor p37, p97 cofactor p37 | |
| Primary ID | Q14CS0 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Adapter protein required for Golgi and endoplasmic reticulum biogenesis (PubMed:17141156). Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis (PubMed:17141156). The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L (PubMed:17141156). VCPIP1 is also required, but not its deubiquitinating activity (PubMed:17141156). Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807). Also, regulates spindle orientation during mitosis (PubMed:23649807). |
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phosphorylation