Summary

Name PLEC
Full Name Plectin
Synonyms PCN, PLTN, Hemidesmosomal protein 1, HD1, Plectin-1 | PLEC1
Primary ID Q15149
Links - -
Type protein
Relations 5
Function Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png phosphorylation PLEC 0.397
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PLEC 0.397
Publications: 2 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation PLEC 0.2
Publications: 1 Organism: Mus Musculus