4.0
Summary
| Name |  DGUOK
|
| Full Name | Deoxyguanosine kinase, mitochondrial |
| Synonyms | dGK | DGK |
| Primary ID | Q16854 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine (PubMed:8692979, PubMed:8706825, PubMed:11687801, PubMed:17073823, PubMed:23043144). In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs (By similarity). Widely used as target of antiviral and chemotherapeutic agents. |