3.0
Summary
| Name |  WASHC4
|
| Full Name | WASH complex subunit 4 |
| Synonyms | Strumpellin and WASH-interacting protein, SWIP, WASH complex subunit SWIP | KIAA1033 |
| Primary ID | Q2M389 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | WASHC4 | form complex 
binding
|
WASH complex | 0.2 |
| Publications: | 1 | |||