+ |
MAJIN | form complex
binding
|
TTM complex |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263303 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
30718482 |
Meiotic specific proteins TERB1, TERB2, and MAJIN form a stable complex that plays a critical role in regulating the recruitment of telomeres to the NE |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SUN1 | up-regulates activity
binding
|
MAJIN |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-263300 |
|
|
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
33015044 |
In this study, we found that SUN1 not only interacted with TERB1 but also interacted with MAJIN, and the interaction of SUN1 with MAJIN is stronger than TERB1. We also found that SUN1 interacted with SPDYA, an activator of CDK2. | It will be of great interest to test this hypothesis to fully understand the mechanisms of stable telomere–NE connection and telomere movement along the NE driven by the LINC complex. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |