Summary

Name ARTN
Full Name Artemin
Synonyms Enovin, Neublastin | EVN
Primary ID Q5T4W7
Links - -
Type protein
Relations 1
Function Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding GFRA3 0.753
Publications: 1 Organism: Homo Sapiens