| Name
|
 MEX3C
|
| Full Name |
RNA-binding E3 ubiquitin-protein ligase MEX3C |
| Synonyms |
RING finger and KH domain-containing protein 2, RING finger protein 194, RING-type E3 ubiquitin transferase MEX3C | RKHD2, RNF194 |
| Primary ID |
Q5U5Q3 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation. |
3.0
ubiquitination