4.0
Summary
| Name |  CARMIL1
|
| Full Name | F-actin-uncapping protein LRRC16A |
| Synonyms | CARMIL homolog, Capping protein regulator and myosin 1 linker protein 1, Capping protein, Arp2/3 and myosin-I linker homolog 1, Capping protein, Arp2/3 and myosin-I linker protein 1, Leucine-rich repeat-containing protein 16A | CARMIL, LRRC16, LRRC16A |
| Primary ID | Q5VZK9 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667). |