4.0
Summary
| Name |  ATAD2
|
| Full Name | ATPase family AAA domain-containing protein 2 |
| Synonyms | AAA nuclear coregulator cancer-associated protein, ANCCA | |
| Primary ID | Q6PL18 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |