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Summary
Name
AATK
Full Name
Serine/threonine-protein kinase LMTK1
Synonyms
Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP | AATYK, KIAA0641, LMR1, LMTK1
Primary ID
Q6ZMQ8
Links
-
-
Type
protein
Relations
2
Function
May be involved in neuronal differentiation.
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by mechanism
none
unknown
binding
by effect
none
down-regulates
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
brain
by cell-line
none
HEK-293 cell
Relations
Regulator
Mechanism
target
score
ℹ
+
AATK
down-regulates
STK39
0.348
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-152921
Homo sapiens
pmid
sentence
17267545
Taken together, our data are consistent with aatyk1 indirectly inhibiting the spak/wnk4 activation of the cotransporter by scaffolding an inhibitory phosphatase in proximity to a stimulatory kinase.
Publications:
1
Organism:
Homo Sapiens
+
AATK
up-regulates
binding
CDK5R1
0.455
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-118403
Homo sapiens
HEK-293 Cell
pmid
sentence
14521924
Apoptosis-associated tyrosine kinase is a cdk5 activator p35 binding protein.
Publications:
1
Organism:
Homo Sapiens
Tissue:
Brain