4.0
Summary
| Name |  SPRED2
|
| Full Name | Sprouty-related, EVH1 domain-containing protein 2 |
| Synonyms | Spred-2 | |
| Primary ID | Q7Z698 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Negatively regulates Ras signaling pathways and downstream activation of MAP kinases (PubMed:15683364). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). |