4.0
Summary
| Name |  GLRX5
|
| Full Name | Glutaredoxin-related protein 5, mitochondrial |
| Synonyms | Monothiol glutaredoxin-5 | C14orf87 |
| Primary ID | Q86SX6 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed:20364084, PubMed:23615440). Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (PubMed:20364084, PubMed:23615440, PubMed:24334290). Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed:20364084). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | GLRX5 | form complex 
binding
|
Mitochondrial BOLA1-GLRX5 iron-sulfur cluster assembly complex | 0.713 |
| Publications: | 1 | |||
| + | GLRX5 | form complex
binding
|
Mitochondrial BOLA3-GLRX5 iron-sulfur cluster assembly complex | 0.742 |
| Publications: | 1 | |||