Summary

Name GPIHBP1
Full Name Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
Synonyms GPI-HBP1, GPI-anchored HDL-binding protein 1, High density lipoprotein-binding protein 1 | HBP1
Primary ID Q8IV16
Links - -
Type protein
Relations 0
Function Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (By similarity). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (By similarity). Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding (PubMed:27929370, PubMed:29899144). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:19304573, PubMed:21314738). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:17997385, PubMed:19304573). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (By similarity).

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