Relation Results

Summary

Name SIAH3
Full Name Seven in absentia homolog 3
Synonyms Siah-3 |
Primary ID Q8IW03
Links - -
Type protein
Relations 1
Function Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dys ...
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Type: Score: Layout: SPV 
0.2Ub:E2SIAH3

Relations

Regulator
Mechanism
target
score
+ up-regulates activity img/direct-activation.png ubiquitination SIAH3 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-271264 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
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