Name	CUL9
Full Name	Cullin-9
Synonyms	CUL-9, UbcH7-associated protein 1, p53-associated parkin-like cytoplasmic protein \| H7AP1, KIAA0708, PARC
Primary ID	Q8IWT3
Links	- -
Type	protein
Relations	4
Function	Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).