Summary

Name MRPL41
Full Name 39S ribosomal protein L41, mitochondrial
Synonyms L41mt, MRP-L41, 39S ribosomal protein L27 homolog, Bcl-2-interacting mitochondrial ribosomal protein L41, Cell proliferation-inducing gene 3 protein, MRP-L27 homolog, Mitochondrial large ribosomal subunit protein mL41 | BMRP, MRPL27, RPML27
Primary ID Q8IXM3
Links - -
Type protein
Relations 1
Function Component of the mitochondrial ribosome large subunit (PubMed:28892042, PubMed:25838379, PubMed:25278503). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding 39S mitochondrial large ribosomal subunit 0.692
Publications: 1 Organism: In Vitro