Name
|
MRPL41
|
Full Name |
39S ribosomal protein L41, mitochondrial |
Synonyms |
L41mt, MRP-L41, 39S ribosomal protein L27 homolog, Bcl-2-interacting mitochondrial ribosomal protein L41, Cell proliferation-inducing gene 3 protein, MRP-L27 homolog, Mitochondrial large ribosomal subunit protein mL41 | BMRP, MRPL27, RPML27 |
Primary ID |
Q8IXM3 |
Links |
- - |
Type |
protein |
Relations |
1 |
Function |
Component of the mitochondrial ribosome large subunit (PubMed:28892042, PubMed:25838379, PubMed:25278503). Also involved in apoptosis and cell cycle (PubMed:16024796, PubMed:16256947). Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins (PubMed:16024796). |