Relation Results

Name	SYNE4
Full Name	Nesprin-4
Synonyms	KASH domain-containing protein 4, KASH4, Nuclear envelope spectrin repeat protein 4 \| C19orf46
Primary ID	Q8N205
Links	- -
Type	protein
Relations	1
Function	As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).